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DigesTip chymo

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DigesTip chymotrypsin is a micro-bioreactor shaped as a pipette tip containing immobilized chymotrypsin. Available in two different formats, DigesTip chymotrypsin is compatible with the majority of 20 μl and 200 μl single-channel and multi-channel pipettors, including: Gilson, Biohit, Rainin, Eppendorf, Brand.

High quality digestion and reduced chymo autolysis DigesTip chymotrypsin performs high quality tryptic digestion with low quantities of samples (up to 10 ng), a considerable reduction of chymotrypsin autolysis and the absence of contaminations.
Reduced tryptic digestion down to 1 minute With DigesTip chymotrypsin, 1 minute is enough! Aspirate the sample to be digested and press and release the plunger repeatedly for one minute.
Verify the result with mass spectrometry: a clear high-coverage spectrum will be obtained!
Usable by robots for high throughput proteomics A lab-automation robot can do this! DigesTip chymotrypsin, being proven for use on a variety of automated liquid handling systems, can be used in automated high-throughput proteomics pipelines.
t;No Unlike other similar products, DigesTip chymotrypsin does not require any preparation phase or any subsequent purification step.

Technical Facts

Protein mixture
Spectrum obtained by digesting with DigesTip chymotrypsin at room temperature for exactly 1 minute a reduced and alkylated three-protein mixture (lysozyme, BSA, transferrin). Digested sample was analyzed by MALDI-TOF MS.
Coverage and number of matched peptides for each protein within the mixture
Protein mixture
Usable by robots

DigesTip chymotrypsin 10 μl is proven for use on a variety of automated liquid handling systems including:

  • Tecan FreedomEVO Workstation
  • Genomic Solutions ProMS MALDI Preparation Station
  • Genomic Solutions ProPrep Protein Digestion and Mass Spec Preparation System
  • Gilson Quad-Z 215 Liquid Handler with Disposable Tips
  • Perkin Elmer TOFPrep MALDI Spotting System
  • CyBio CyBi - Well 96 Automated Pipettor.

DigesTip chymotrypsin can improve the performance of an automated high-throughput proteomics pipeline, adding value to your investment.

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